VIPER R-System Package
Download VIPER
Download VIPER from Bioconductor.
Installation
Please install VIPER according to the instructions on Bioconductor.
bcellViper data package
The bcellViper data package is required to run the examples in the documentation and vignette of the viper package. Please install this package before installing viper.
Additional regulatory networks
Human B-cell transcriptional regulatory network based on Affymetrix U95Av2 platform
Human B-cell transcriptional regulatory network based on Affymetrix U133plus2 platform
Human glioma transcriptional regulatory network
MCF7 human breast carcinoma cell line transcriptional regulatory network
Human breast carcinoma signalome regulatory network
Reference
Alvarez MJ, Shen Y, Giorgi FM, Lachmann A, Ding BB, Ye BH, Califano A. Functional characterization of somatic mutations in cancer using network-based inference of protein activity. Nat Genet. 2016 Jun 20. [Epub ahead of print]