Networks

The following interactome regulatory networks are available for download.

TCGA-AML-TF

The transcriptional network derived using ARACNe on gene expression measurements from primary samples derived from acute myeloid leukemia patients patients, provided by TCGA.

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TCGA-AML-SIG

A network providing the genes that are most affected transcriptionally downstream by changes in signaling molecules. The network was derived by applying ARACNe to gene expression measurements measured in primary samples derived from acute myeloid leukemia patients patients, provided by TCGA.

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Bcell-U95av2

Human B-cell interactome. The transcriptional interactions were derived from 254 B cell lymphoma gene expression profiles on U95av2 arrays, and integrated with a protein-protein network using naive Bayesian integration to obtain an interactome.

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Bcell-U133p2

Human B-cell interactome. The transcriptional interactions derived from 226 B cell lymphoma gene expression profiles on U133p2 array, and integrated with a protein-protein network using naive Bayesian integration to obtain an interactome.

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BRCA-MCF7

A human breast cancer interactome. The transcriptional network was derived from gene expression profiles of 448 breast cancer patients, which were obtained from the CMAP2 dataset. Sample selection was done to remove redundancy and quality control, and the network was integrated with protein-protein networks using naive Bayse integration to obtain an interactome.

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